Review
"This book is most timely and should be an essential component for all investigators involved in cell culture research."
—John Bennett, University of Rochester Medical Center (2002)


Review
"This book is most timely and should be an essential component for all investigators involved in cell culture research."
—John Bennett, University of Rochester Medical Center (2002)


Book Description
This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references.

Key Features
* the full spectrum of malignant cell lines from all hematopoietic cell lineages
* sister cell lines and relevant subclones
* clinical data: patient, diagnosis, treatment status, and specimen source
* authentication of derivation and availability
* immunophenotype
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* cell cultures aspects: establishment, medium, doubling time, growth
* cytochemical profile
* cytokine production and response to cytokines
* proto-oncogene and transcription factor expression/alteration
* functional features: differentiation induction, heterotransplantability
* special unique features
* key references


Book Info
German Collection of Microorganisms and Cell Cultures, Braunschweig. Comprehensive reference manual to current well-characterized leukemia-lymphoma cell lines. Includes more than 400 individual entries covering clinical, immunological, and genetic and functional data. Softcover.


From the Publisher
Praise for the Series "...a growing series of excellent manuals." (Molecular Medicine Today) "...essential works of reference..." Trends in Biochemical Sciences)


From the Back Cover
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Leukemia-Lymphoma Cell Line FactsBook is the most comprehensive and essential reference manual for all current well-characterised leukemia-lymphoma cell lines. Introductory chapters provide background and perspective for culturing malignant hematopoietic cell lines. This is followed by over 400 comprehensive individual entries covering essential clinical, immunological, genetic and functional data. Information is also provided on partly characterised leukemia-lymphoma cell lines, growth factor-dependent cell lines, cell lines with unique chromosomal alterations, and recommended reference cell lines.
Entries provide information on:
* the full spectrum of malignant cell lines from all hematopoietic cell lineages
* sister cell lines and relevant subclones
* clinical data: patient, diagnosis, treatment status, and specimen source
* authentication of derivation and availability
* immunophenotype
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* cell cultures aspects: establishment, medium, doubling time, growth
* cytochemical profile
* cytokine production and response to cytokines
* proto-oncogene and transcription factor expression/alteration
* functional features: differentiation induction, heterotransplantability
* special unique features
* key references

ANNOTATION

Audience: Research level scientists and clinicians in Immunology, Cell Biology, Genetics, Molecular Biology, Hematology, Oncology, Pharmacology, Toxicology, Biochemistry, and Virology.

FROM THE PUBLISHER

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the FactsBooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Leukemia-Lymphoma Cell Line FactsBook is the most comprehensive and essential reference manual for all current well-characterised leukemia-lymphoma cell lines. Introductory chapters provide background and perspective for culturing malignant hematopoietic cell lines. This is followed by over 400 comprehensive individual entries covering essential clinical, immunological, genetic and functional data. Information is also provided on partly characterised leukemia-lymphoma cell lines, growth factor-dependent cell lines, cell lines with unique chromosomal alterations, and recommended reference cell lines.
Entries provide information on:
* the full spectrum of malignant cell lines from all hematopoietic cell lineages
* sister cell lines and relevant subclones
* clinical data: patient, diagnosis, treatment status, and specimen source
* authentication of derivation and availability
* immunophenotype
* cytogenetic karyotype
* translocations and fusion genes
* receptor gene rearrangements and genetic alterations
* cell cultures aspects: establishment, medium, doubling time, growth
* cytochemical profile
* cytokine production and response to cytokines
* proto-oncogene and transcription factor expression/alteration
* functional features: differentiation induction, heterotransplantability
* special unique features
* key references

SYNOPSIS

This book represents an essential reference manual for all of the well-characterized leukemia-lymphoma cell lines currently available. It provides the most important facts, using the succinct and user-friendly format that has made the FactsBooks so popular with scientists and clinical researchers. Introductory chapters provide background and perspective for culturing malignant hematopoietic (blood forming) cell lines. These chapters are followed by over 400 comprehensive individual entries. Each cell line entry highlights essential clinical, immunological, genetic, and functional features and includes a comprehensive listing of references.

ACCREDITATION