Book Description
Helicobacter pylori: Biology and Clinical Practice is the first book to fully describe H. pylori and the pathogenesis of H. pylori infections. It delineates the genome of H. pylori, discusses the molecular biology of the unique urease enzyme, and examines the clinical application of these discoveries. The book describes the epidemiology of H. pylori and its relevance to gastric cancer, and it offers clear guidance to clinicians for the diagnosis and treatment of peptic ulcer and non-ulcer dyspepsia in adults and children. Vaccine principles and possibilities are presented for the first time. Edited by the leader of the microbiology team that achieved the first culture of H. pylori, and named the Helicobacter genus, this book is essential for bacteriologists, gastroenterologists, microbiologists, infectious disease specialists, and other researchers interested in H. pylori.

ANNOTATION

This book contains black-and-white illustrations.

FROM THE CRITICS

Michael D. Brown

This book was edited by two microbiologists instrumental in the discovery and characterization of the Helicobacter organisms. The intent is a comprehensive book covering the microbiology, pathophysiology, and clinical significance of H. pylori. The stated purpose of this text is a comprehensive review of H. pylori that devotes equal time to the clinical aspects and the microbiology and molecular biology of the organism. The stated audience is microbiologists and gastroenterologists; however, practicing gastroenterologists will probably not find the book useful unless they are involved in the research aspects of this organism. It is slanted toward the microbiologist and, given the rapid changes occurring with the clinical role of H. pylori, the gastroenterologist looking for the most current diagnostic and treatment opinions would be better served by recent medical journals. The book is richly-illustrated with excellent quality illustrations and photographs. The book's chapters are organized into the microbiology of H. pylori, its role in the pathophysiology of peptic ulcer disease, and therapeutic approaches. Chapters are well referenced with very current citations, particularly important in this rapidly changing area. It has unique chapters that deal with the animal models of H. pylori infection, genome mapping, and vaccine development. This well-edited book has the consistency of writing style characteristic of a single-authored text. The index is complete and useful. The book contains methods that will be useful to those involved in basic research concerning H. pylori. The authors have constructed an extremely detailed yet readable textthat is essential for any microbiologist or gastroenterologist with a basic or clinical research interest in H. pylori. Coverage of the microbiologic aspects of H. pylori is its strong point. It only suffers in that this is a rapidly evolving area of interest in the pathogenesis of peptic ulcer disease, and therefore cannot contain the latest changes regarding diagnosis and therapy. These latter areas would be of primary interest to the practicing gastroenterologist.

Doody Review Services

Reviewer: Michael D. Brown, MD (Rush-Presbyterian-St. Luke's Medical Center)Description: This book was edited by two microbiologists instrumental in the discovery and characterization of the Helicobacter organisms. The intent is a comprehensive book covering the microbiology, pathophysiology, and clinical significance of H. pylori. Purpose: The stated purpose of this text is a comprehensive review of H. pylori that devotes equal time to the clinical aspects and the microbiology and molecular biology of the organism. Audience: The stated audience is microbiologists and gastroenterologists; however, practicing gastroenterologists will probably not find the book useful unless they are involved in the research aspects of this organism. It is slanted toward the microbiologist and, given the rapid changes occurring with the clinical role of H. pylori, the gastroenterologist looking for the most current diagnostic and treatment opinions would be better served by recent medical journals. Features: The book is richly-illustrated with excellent quality illustrations and photographs. The book's chapters are organized into the microbiology of H. pylori, its role in the pathophysiology of peptic ulcer disease, and therapeutic approaches. Chapters are well referenced with very current citations, particularly important in this rapidly changing area. It has unique chapters that deal with the animal models of H. pylori infection, genome mapping, and vaccine development. This well-edited book has the consistency of writing style characteristic of a single-authored text. The index is complete and useful. The book contains methods that will be useful to those involved in basic research concerning H. pylori. Assessment: The authors have constructed an extremely detailed yet readable text that is essential for any microbiologist or gastroenterologist with a basic or clinical research interest in H. pylori. Coverage of the microbiologic aspects of H. pylori is its strong point. It only suffers in that this is a rapidly evolving area of interest in the pathogenesis of peptic ulcer disease, and therefore cannot contain the latest changes regarding diagnosis and therapy. These latter areas would be of primary interest to the practicing gastroenterologist.

RATING

3 Stars from Doody

ACCREDITATION

Goodwin, C. Stewart, MD, Dip Bact (United Arab Emirates Univ); Worsley, Bryan W., PhD (United Arab Emirates Univ)