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Instructs investigators in key genetic, cellular, and molecular biological methods of analyzing colorectal tumors. Techniques and assays are described in detail to allow researchers to experiment on colon tumors. Most chapters are written by scientists who pioneered the methods presented. Coverage includes gross microdissection of colon tumors, establishment of cell lines and xenografted tumors, chromosomal analyses such as FISH assays, mutational analyses of colon tumors and blood samples, gene expression analyses, and microsatellite instability testing. Includes a few color images. For researchers at various levels, from graduate students to professionals. Powell is affiliated with the University of Virginia Health System.Book News, Inc.®, Portland, OR


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Univ. of Virginia, Charlottesville. Provides cancer investigators with a collection of all the key genetic, cellular, and molecular biological methods for analyzing colon cancer today. Includes step-by-step instructions and notes on pitfalls to avoid. Outline format. DNLM: Colorectal Neoplasms--pathology.

ANNOTATION

"...leading clinical researchers provide state-of-the-art methods for analyzing colorectal tumors discussing recent advances in related fields, instability testing, chromosomal studies & gene expression analysis."

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